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| Status |
Public on Mar 10, 2020 |
| Title |
Evaluation of Eribulin Combined with Irinotecan for Treatment of Pediatric Cancer Xenografts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Eribulin, irinotecan, and the combination were studied in ES4 xenograft model. RNAs from xenograft tumors were harvested at 24h and 144h after single agent or combination treatment to analyze gene expression.
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| Overall design |
Gene expression profiles were generated using RNA-seq with 3 replicates at each time point (3 tumors from 3 separate mice) and 3 control samples (no treatment).
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| Contributor(s) |
Robles AJ, Kurmasheva RT, Bandyopadhyay A, Phelps DA, Erickson S, Lai Z, Kurmashev D, Chen Y, Smith MA, Houghton PJ |
| Citation(s) |
32184294 |
| Submission date |
Mar 09, 2020 |
| Last update date |
Nov 25, 2020 |
| Contact name |
Yidong Chen |
| E-mail(s) |
cheny8@uthscsa.edu
|
| Phone |
2105629163
|
| Organization name |
UT Health Science Center at San Antonio
|
| Department |
Population Health Sciences
|
| Street address |
8403 Floyd Curl Drive, MSC 7784
|
| City |
San Antonio |
| State/province |
Texas |
| ZIP/Postal code |
78229 |
| Country |
USA |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA611620 |
| SRA |
SRP252131 |
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