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| Status |
Public on Mar 09, 2020 |
| Title |
Serum microRNA profiles and functional enrichment analysis in comorbidity between Arnold-Chiari and Tourette syndromes: insights into their related pathological pathways |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
To identify the differential expression of serum microRNA as molecular fingerprints for Arnold-Chiari (AC) and Tourette syndromes (TS), also in comorbid status between both disorders (ACTS).
To investigate on differentially expressed miRNA associations with the neuropsychological and neuroimaging parameters for each participant and their potential involvement in AC and TS pathological pathways.
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| Overall design |
This study profiled the miRNA expression in sera of 10 AC patients, 11 ACTS patients, 6 TS patients and 8 unaffected controls (NC)
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| Contributor(s) |
Mirabella F, Gulisano M, Capelli M, Lauretta G, Cirnigliaro M, Palmucci S, Stella M, Barbagallo D, Di Pietro C, Purrello M, Ragusa M, Rizzo R |
| Citation(s) |
33469418 |
| |
| Submission date |
Mar 06, 2020 |
| Last update date |
Jan 27, 2021 |
| Contact name |
Marco Ragusa |
| Organization name |
University of Catania
|
| Department |
Biomedical and Biotechnological Sciences
|
| Street address |
Via Santa sofia 87
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| City |
Catania |
| ZIP/Postal code |
95030 |
| Country |
Italy |
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| Platforms (1) |
| GPL24158 |
NanoString nCounter Human v3 miRNA Assay (NS_H_miR_v3a) |
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| Samples (35)
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| Relations |
| BioProject |
PRJNA610790 |
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