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Series GSE145083 Query DataSets for GSE145083
Status Public on Jan 19, 2021
Title miRNA expression profiling in a murine model of KrasG12D induced CMML-like MPD
Platform organism synthetic construct
Sample organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary Mx1-Cre/KrasG12D mice were injected with pIpC to induce a myeloproliferative disease resembling human chronic myelomonocytic leukemia (CMML-like MPD). When the disease was fully developed, CD11b-/Ly6G-/c-Kit+ hematopoietic stem and progenitor cells (HSPCs) were isolated and subjected to miR-microarray expression profiling. pIpC-injected CD11b-/Ly6G-/c-Kit+ HSPCs of age matched wildytpe control mice were used as controls.
Overall design n=4 (KrasG12D vs. Wt)
Contributor(s) Berg JL, Zebisch A
Citation(s) 33407852
Submission date Feb 11, 2020
Last update date Jan 19, 2021
Contact name Karin Wagner
Organization name Medical University Graz
Department Molecular Biology
Street address Stiftingtalstrasse 24
City Graz
State/province Styria
ZIP/Postal code 8010
Country Austria
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (8)
GSM4306236 total RNA from sorted BM, wt-942
GSM4306237 total RNA from sorted BM, wt-978
GSM4306238 total RNA from sorted BM, wt-984
BioProject PRJNA605975

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE145083_RAW.tar 5.4 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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