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Status |
Public on Jan 19, 2021 |
Title |
miRNA expression profiling in a murine model of KrasG12D induced CMML-like MPD |
Platform organism |
synthetic construct |
Sample organism |
Mus musculus |
Experiment type |
Non-coding RNA profiling by array
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Summary |
Mx1-Cre/KrasG12D mice were injected with pIpC to induce a myeloproliferative disease resembling human chronic myelomonocytic leukemia (CMML-like MPD). When the disease was fully developed, CD11b-/Ly6G-/c-Kit+ hematopoietic stem and progenitor cells (HSPCs) were isolated and subjected to miR-microarray expression profiling. pIpC-injected CD11b-/Ly6G-/c-Kit+ HSPCs of age matched wildytpe control mice were used as controls.
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Overall design |
n=4 (KrasG12D vs. Wt)
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Contributor(s) |
Berg JL, Zebisch A |
Citation(s) |
33407852 |
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Submission date |
Feb 11, 2020 |
Last update date |
Jan 19, 2021 |
Contact name |
Karin Wagner |
E-mail(s) |
kar.wagner@medunigraz.at
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Organization name |
Medical University Graz
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Department |
Molecular Biology
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Street address |
Stiftingtalstrasse 24
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City |
Graz |
State/province |
Styria |
ZIP/Postal code |
8010 |
Country |
Austria |
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Platforms (1) |
GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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Samples (8)
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Relations |
BioProject |
PRJNA605975 |
Supplementary file |
Size |
Download |
File type/resource |
GSE145083_RAW.tar |
5.4 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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