|
| Status |
Public on Mar 01, 2020 |
| Title |
Pancreatic Circulating Tumour Cell Profiling Identifies LIN28B as a Metastasis Driver and Drug Target |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Gene expression profiling of circulating tumor cells purified from human patients with pancreatic cancer led to identification of LIN28B as possible metastasis driver. Functional studies in model systems confirmed the importance of this pathway.
|
| |
|
| Overall design |
RNA-seq of primary purified circulating tumor cells from pancreatic cancer patients and healthy donors.
|
| |
|
| Contributor(s) |
Franses J, Ting D |
| Citation(s) |
32620742 |
| |
| Submission date |
Jan 30, 2020 |
| Last update date |
Jul 13, 2020 |
| Contact name |
David T Ting |
| E-mail(s) |
dting1@partners.org
|
| Phone |
617-726-0337
|
| Organization name |
Massachusetts General Hospital
|
| Department |
Cancer Center
|
| Lab |
Ting Lab
|
| Street address |
149 E 13th street
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02129 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (81)
|
|
| Relations |
| BioProject |
PRJNA604022 |
| SRA |
SRP246180 |
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