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Series GSE14312 Query DataSets for GSE14312
Status Public on Jan 07, 2010
Title Microarray Analysis of Genes Regulated by Macrophage-Conditioned Media Treatment of Human Adipocytes
Organism Homo sapiens
Experiment type Expression profiling by array
Summary A major development in obesity research is the recognition that the condition is characterized by chronic mild inflammation. Within adipose tissue, this involves the infiltration of macrophages as well as a direct inflammatory response of adipocytes. This study has used Agilent whole-genome microarrays to examine the effects of macrophage-conditioned medium on the global inflammatory response of human adipocytes.
Overall design Human adipocytes (SGBS cells), differentiated in culture, were treated with macrophage (U937 cells) conditioned media for 4 or 24 h. Control SGBS cells were treated with unconditioned media (control) or RPMI media alone to control for differences in media used to culture U937 cells. There were 6 replicates per group.
Contributor(s) O’Hara A, Lim FL, Mazzatti DJ, Trayhurn P
Citation(s) 19585142
Submission date Jan 07, 2009
Last update date Feb 22, 2018
Contact name Fei Ling Lim
Phone +44 (0)1234222450
Organization name Unilever
Street address Colworth Science Park
City Sharnbrook
State/province Bedfordshire
ZIP/Postal code MK44 1LQ
Country United Kingdom
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (36)
GSM357545 SGBS_adipocytes_U937 media_4h_rep2
GSM357546 SGBS_adipocytes_control media_24h_rep2
GSM357547 SGBS_adipocytes_RPMI media_24h_rep2
BioProject PRJNA111311

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Supplementary file Size Download File type/resource
GSE14312_RAW.tar 283.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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