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Series GSE142405 Query DataSets for GSE142405
Status Public on May 29, 2020
Title Rational and scalable strategies to identify small “molecular glue” degraders
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In our effort to characterize putatite novel molecular glues that we found in a phenotypic screen, we wanted to gain a more detailed understanding of the effects of these small-molecules at the trascriptome level.
Overall design KBM7 cells treated for 5h with DMSO, dCeMM-1[Hit4], dCeMM-2[Hit1], dCeMM-3[Hit2], dCeMM-4[Hit8] (10xEC50) and THZ531 (600nM). Triplicates per condition.
Contributor(s) Mayor-Ruiz C, Bauer S, Imrichova H, Winter G
Citation(s) 32747809
Submission date Dec 20, 2019
Last update date Aug 26, 2020
Contact name Hana Imrichova
Organization name CeMM, Vienna
Street address Lazarettgasse 14, AKH BT 25.3
City Vienna
ZIP/Postal code 1090
Country Austria
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (18)
GSM4227024 DMSO_rep1
GSM4227025 DMSO_rep2
GSM4227026 DMSO_rep3
BioProject PRJNA596945
SRA SRP238337

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE142405_RAW.tar 3.4 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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