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Status |
Public on Aug 23, 2020 |
Title |
ChIP-seq analysis of Ssrp1 and Usp7 in mESCs |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
FACT was discovered to be a repressor of transcription in mES cells. In addition, the murine endogenous retrovirus were repressed by various mechanisms. Hence, we examined the possibility for Ssrp1 as a repressor of MT2/MERVL.
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Overall design |
We performed CHIP-seq analysis in order to identifiy the binding sites of Ssrp1 in wild-type mESCs and perform enrichment analysis of Usp7 after Ssrp1 knockout.
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Contributor(s) |
Chen F, Zhang W, Lu X |
Citation(s) |
32894293 |
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Submission date |
Dec 10, 2019 |
Last update date |
Oct 26, 2020 |
Contact name |
Weiyu Zhang |
E-mail(s) |
ch8316f5eyu@gmail.com
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Phone |
18902012072
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Organization name |
Nankai University
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Street address |
No.38 Tongyan Road, Jinnan District
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City |
Tainjin |
ZIP/Postal code |
300350 |
Country |
China |
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Platforms (1) |
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Samples (8)
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Relations |
BioProject |
PRJNA594736 |
SRA |
SRP235597 |