|
| Status |
Public on Jan 10, 2020 |
| Title |
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We used RNA_Seq to quantify cellular transcripts in human spontaneously immortalized HaCaT keratinocytes upon knock out of GALNT1, GALNT2, or GALNT3 - most abundantly expressed enzyme isoforms initiating mucin-type O-linked glycosylation.
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| |
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| Overall design |
3 different knock out clones of each GALNT1, GALNT2, or GALNT3, as well as 2 biological replicates of wild type
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| |
|
| Contributor(s) |
Pallesen EH, Bagdonaite I, Joshi HJ |
| Citation missing |
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| |
| Submission date |
Dec 03, 2019 |
| Last update date |
Jan 10, 2020 |
| Contact name |
Hiren J Joshi |
| E-mail(s) |
joshi@sund.ku.dk
|
| Organization name |
Copenhagen University
|
| Department |
ICMM
|
| Lab |
Copenhagen Center for Glycomics
|
| Street address |
Blegdamsvej 3B
|
| City |
Copenhagen N |
| ZIP/Postal code |
2200 |
| Country |
Denmark |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (11)
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| Relations |
| BioProject |
PRJNA593247 |
| SRA |
SRP234568 |
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