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Series GSE141277 Query DataSets for GSE141277
Status Public on Sep 28, 2022
Title Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [4C-Seq]
Organism Homo sapiens
Experiment type Other
Summary The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD).
Overall design 4C-seq analysis of SNCA promoter interact regions
Contributor(s) Cheng F, Riess O
Citation(s) 35015830
BioProject PRJNA591445
Submission date Dec 02, 2019
Last update date Sep 29, 2022
Contact name Fubo Cheng
Organization name University of Tuebingen
Department Institute of Medical Genetics and Applied Genomics
Street address Calwerstrasse 7
City Tuebingen
ZIP/Postal code 72076
Country Germany
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (6)
GSM4200330 4C-seq wild-type repeat 1
GSM4200331 4C-seq wild-type repeat 2
GSM4200332 4C-seq CTCF KO repeat 1
This SubSeries is part of SuperSeries:
GSE141278 Transcription regulation of SNCA by dystonia type 6 gene product THAP1
SRA SRP232957

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE141277_RAW.tar 90.0 Kb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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