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| Status |
Public on Nov 11, 2022 |
| Title |
Dynamic transcriptome profiling of mouse spleen infected with extraintestinal pathogenic Escherichia coli |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Extraintestinal pathogenic Escherichia coli (ExPEC) is a common bacterial strain causing diverse diseases in humans and animals. To analyse the detailed mechanisms underlying ExPEC-mediated sepsis in humans, the transcriptome response of mice at 3h,6h, and 12h after ExPEC infection was analyzed by RNA-seq of mouse spleen samples.
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| Overall design |
The transcriptome response of mice to intraperitoneal injection with ExPEC was analyzed by RNA-seq of mouse spleen samples.
4 groups with 3 biological replicates, 3P1-3 for the PBS-injected group at 3 hpi (designated g1), 3X1-3 for the ExPEC-infected group at 3 hpi (designated g2), 6X1-3 for the ExPEC-infected group at 6 hpi (designated g3), and 12X1-3 for the ExPEC-infected group at 12 hpi (designed g4).
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| Contributor(s) |
Ren H, Chen X |
| Citation missing |
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| |
| Submission date |
Nov 19, 2019 |
| Last update date |
Nov 11, 2022 |
| Contact name |
ren haiyan |
| E-mail(s) |
renhaiyan0313@outlook.com
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| Organization name |
Nanjing Agricultural university
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| Street address |
No. 1 Weigang, Nanjing, China
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| City |
nanjing |
| ZIP/Postal code |
21195 |
| Country |
China |
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| Platforms (1) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA590356 |
| SRA |
SRP230601 |
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