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Series GSE140637 Query DataSets for GSE140637
Status Public on Nov 11, 2022
Title Dynamic transcriptome profiling of mouse spleen infected with extraintestinal pathogenic Escherichia coli
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Extraintestinal pathogenic Escherichia coli (ExPEC) is a common bacterial strain causing diverse diseases in humans and animals. To analyse the detailed mechanisms underlying ExPEC-mediated sepsis in humans, the transcriptome response of mice at 3h,6h, and 12h after ExPEC infection was analyzed by RNA-seq of mouse spleen samples.
Overall design The transcriptome response of mice to intraperitoneal injection with ExPEC was analyzed by RNA-seq of mouse spleen samples.
4 groups with 3 biological replicates, 3P1-3 for the PBS-injected group at 3 hpi (designated g1), 3X1-3 for the ExPEC-infected group at 3 hpi (designated g2), 6X1-3 for the ExPEC-infected group at 6 hpi (designated g3), and 12X1-3 for the ExPEC-infected group at 12 hpi (designed g4).
Contributor(s) Ren H, Chen X
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Submission date Nov 19, 2019
Last update date Nov 11, 2022
Contact name ren haiyan
Organization name Nanjing Agricultural university
Street address No. 1 Weigang, Nanjing, China
City nanjing
ZIP/Postal code 21195
Country China
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (12)
GSM4176085 3P1
GSM4176086 3P2
GSM4176087 3P3
BioProject PRJNA590356
SRA SRP230601

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE140637_gene_expression_anno.txt.gz 12.9 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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