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Series GSE138504 Query DataSets for GSE138504
Status Public on Oct 07, 2019
Title Nivolumab treatment for relapsed/refractory Epstein-Barr virus-associated hemophagocytic lymphohistocytosis in adults
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Single cell RNA sequencing (scRNA-seq) was performed with peripheral blood cells before (Day 0, T0), during nivolumab treatment (Day 7, T1; Day 21, T2), and when plasma EBV turned negative (Day 76, T3) in 1 patient (patient 7). scRNA-seq libraries were generated following the recommended protocol of the 3’ scRNA-seq 10X genomics platform and using v2 chemistry, and sequenced data was collected by illumina NovaSeq 6000 sequencing.
 
Overall design Single cell RNA sequencing (scRNA-seq) in 4 stages
 
Contributor(s) Liu P, Pan X, Chen C, Niu T, Shuai X, Wang J, Chen X
Citation(s) 31914172
Submission date Oct 07, 2019
Last update date Apr 02, 2020
Contact name Xaingyu Pan
E-mail(s) pangxueyu233@outlook.com
Organization name Sichuan University
Department State Key Laboratory of Biotherapy, West China Hospital, Sihcuan University.
Lab Chen & Liu Lab
Street address No.17 Renming road section3
City Chengdu, Cihna
State/province Sichuan
ZIP/Postal code 610041
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM4110026 HLH_T1_scRNAseq
GSM4110027 HLH_T2_scRNAseq
GSM4110028 HLH_T3_scRNAseq
Relations
BioProject PRJNA576213
SRA SRP224614

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE138504_RAW.tar 1.0 Gb (http)(custom) TAR (of RDS, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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