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Series GSE138504 Query DataSets for GSE138504
Status Public on Oct 07, 2019
Title Nivolumab treatment for relapsed/refractory Epstein-Barr virus-associated hemophagocytic lymphohistocytosis in adults
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Single cell RNA sequencing (scRNA-seq) was performed with peripheral blood cells before (Day 0, T0), during nivolumab treatment (Day 7, T1; Day 21, T2), and when plasma EBV turned negative (Day 76, T3) in 1 patient (patient 7). scRNA-seq libraries were generated following the recommended protocol of the 3’ scRNA-seq 10X genomics platform and using v2 chemistry, and sequenced data was collected by illumina NovaSeq 6000 sequencing.
Overall design Single cell RNA sequencing (scRNA-seq) in 4 stages
Contributor(s) Liu P, Pan X, Chen C, Niu T, Shuai X, Wang J, Chen X
Citation(s) 31914172
Submission date Oct 07, 2019
Last update date Apr 02, 2020
Contact name Xaingyu Pan
Organization name Sichuan University
Department State Key Laboratory of Biotherapy, West China Hospital, Sihcuan University.
Lab Chen & Liu Lab
Street address No.17 Renming road section3
City Chengdu, Cihna
State/province Sichuan
ZIP/Postal code 610041
Country China
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM4110026 HLH_T1_scRNAseq
GSM4110027 HLH_T2_scRNAseq
GSM4110028 HLH_T3_scRNAseq
BioProject PRJNA576213
SRA SRP224614

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE138504_RAW.tar 1.0 Gb (http)(custom) TAR (of RDS, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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