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Series GSE137621 Query DataSets for GSE137621
Status Public on Jul 08, 2020
Title Genome-wide analysis of methylated DNA in control and Tet2/Tet3-deficient B cells
Organism Mus musculus
Experiment type Methylation profiling by high throughput sequencing
Summary We report the global DNA methylation status in B cells. We found that DNA demethylation occurred around gene promoters and Tet-dependent demethylation sites at the genome-wide manner. This study provides a basis for the comprehensive understanding of role of Tet2 and Tet3 in DNA demethylation-dependent regulation of transcription in B cells.
 
Overall design Examination of global DNA methylation status in control and Tet2/Tet3-deficient B cells
 
Contributor(s) Tanaka S, Miura F
Citation(s) 32572241
Submission date Sep 17, 2019
Last update date Jul 08, 2020
Contact name SHINYA TANAKA
Organization name Kyushu University
Street address 3-1-1, maidashi, Higashi-ku
City Fukuoka
ZIP/Postal code 812-8582
Country Japan
 
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (4)
GSM4083370 Bisulfite-seq CTL-1
GSM4083371 Bisulfite-seq CTL-2
GSM4083372 Bisulfite-seq TetDKO-1
Relations
BioProject PRJNA566023
SRA SRP222128

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE137621_RAW.tar 1.8 Gb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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