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| Status |
Public on Sep 09, 2022 |
| Title |
ARRB1 inhibits the progression of non-alcoholic steatohepatitis by promoting the intracellular processing of GDF15 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
ARRB1 is a vital regulator in the development of NASH via facilitating GDF15 translocate to Golgi apparatus and maturation. ARRB1 is a potential therapeutic target for the treatment of NASH.
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| Overall design |
Hepatocytes mRNA profiles of ARRB1-/- and WT mice fed with HFD for 26 weeks were generated by deep sequencing, in triplicate.
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| Contributor(s) |
Zhang Z, Sun B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 09, 2019 |
| Last update date |
Sep 09, 2022 |
| Contact name |
Zechuan Zhang |
| E-mail(s) |
zechuanzhang@outlook.com
|
| Organization name |
Nanjing Medical University
|
| Street address |
Zhongshan Road
|
| City |
Nanjing |
| ZIP/Postal code |
210008 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA564574 |
| SRA |
SRP221061 |
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