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| Status |
Public on Nov 22, 2008 |
| Title |
Effect of an anti-myostatin antibody on skeletal muscle gene expression in mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
More than 2,000 genes appear to be upregulated or downregulated in skeletal muscle of mice with constitutive knockout of myostatin (Steelman et al., FASEB J 20:580-2, 2006). This study was done to determine whether inhibition of myostatin activity in mature mice has similar effects on the pattern of gene expression.
Keywords: Differential expression in treated and control mice
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| Overall design |
Ten samples from JA16 antibody-treated mice were compared with 10 samples from saline-treated mice
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| Contributor(s) |
Welle S |
| Citation(s) |
19141683 |
| |
| Submission date |
Nov 21, 2008 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Stephen Welle |
| E-mail(s) |
swelle@rochester.rr.com
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| Organization name |
University of Rochester
|
| Street address |
601 Elmwood Avenue
|
| City |
Rochester |
| State/province |
NY |
| ZIP/Postal code |
14642 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA109439 |
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