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Series GSE136415 Query DataSets for GSE136415
Status Public on Sep 17, 2019
Title A comparison of evolutionary changes and constraints on gene regulation between fin and limb development [ATAC-seq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We report time-series transcriptome of developing bamboo shark fin buds and mouse forelimb buds, and open chromatin regions of developing mouse forelimb buds. The major contributions of this study are 1) transcriptomic data with an accurate orthology map for a systematic comparison between the two species; 2) high quality chromatin accessibility data for mouse limb development; 3) discovery of mass heterochronic genes between fins and limbs; 4) hourglass-shaped conservation between fins and limbs, providing insights into a general trend of gene regulatory evolution.
Overall design ATAC-seq analyses of mouse limb development
Contributor(s) Onimaru K, Tatsumi K, Tanegashima C, Kadota M, Nishimura O, Kuraku S
Citation(s) 33560225
Submission date Aug 27, 2019
Last update date Mar 16, 2021
Contact name Koh Onimaru
Phone 484679398
Organization name Center for Biosystems Dynamics Research
Lab Laboratory for Bioinformatics Research
Street address 312 Information Science Building, 2-1 Hirosawa
City Wako
State/province Saitama
ZIP/Postal code 351-0198
Country Japan
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (13)
GSM4048688 ATAC-seq E09.5 replicate 1
GSM4048689 ATAC-seq E09.5 replicate 2
GSM4048690 ATAC-seq E09.5 replicate 3
This SubSeries is part of SuperSeries:
GSE136445 A comparison of evolutionary changes and constraints on gene regulation between fin and limb development
BioProject PRJNA562519
SRA SRP219910

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136415_RAW.tar 1.5 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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