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| Status |
Public on Aug 23, 2019 |
| Title |
miRNA profiling from different histological subtypes of colorectal carcinoma |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Colorectal cancer (CRC) is the third leading cause of cancer mortality worldwide. Different pathological pathways and molecular drivers have been described and some of the associated markers are used to select effective anti-neoplastic therapy. This dataset is part of ColPortal, a platform that integrates transcriptomic, microtranscriptomic, methylomic and microbiota data of patients with colorectal cancer. ColPortal also includes information of histological features and digital histological slides from the study cases.
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| Overall design |
In this study, we used miRNA expression arrays (Affymetrix GeneChip miRNA 3.0 arrays (Affymetrix, Inc., Santa Clara, CA, USA) containing 5,607 probe sets for human pre-miRNA, miRNAs, small nuclear RNA, and small Cajal body-specific RNA) to investigate differences between different histological subtypes of colorectal carcinomas (i.e. conventional carcinoma (CC), serrated adenocarcinoma (SAC) and colorectal carcinoma having histological and molecular features of microsatelite instability (hmMSI-H))
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| Contributor(s) |
Esteban-Gil A, Pérez-Sanz F, García-Solano J, Alburquerque-González B, Parreño-González MA, del Carmen Legaz-García M, Rodriguez-Braun E, Pimentel P, Slaby O, Conesa-Zamora P |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Aug 22, 2019 |
| Last update date |
Aug 25, 2019 |
| Contact name |
Angel Esteban-Gil |
| E-mail(s) |
angel.esteban@ffis.es
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| Phone |
+34868885229
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| Organization name |
Institute for Biomedical Research of Murcia (IMIB)
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| Department |
Biomedical Informatics and Bioinformatics Platform
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| Street address |
Campus de Ciencias de la Salud Carretera Buenavista s/n
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| City |
Murcia |
| State/province |
Murcia |
| ZIP/Postal code |
30120 |
| Country |
Spain |
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| Platforms (1) |
| GPL16384 |
[miRNA-3] Affymetrix Multispecies miRNA-3 Array |
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| Samples (30)
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| Relations |
| BioProject |
PRJNA561571 |
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