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Series GSE135119 Query DataSets for GSE135119
Status Public on Nov 12, 2019
Title Microarray profiling identifies extracellular circulating miRNAs dysregulated in cystic fibrosis
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Extracellular circulating miRNAs (ECmiRNAs) play a crucial role in cell-to-cell communication and serve as non-invasive biomarkers in a wide range of diseases, but their abundance and functional relevance in cystic fibrosis (CF) remain poorly understood.
Microarray technology was employed to identify aberrantly expressed plasma ECmiRNAs in CF and elucidate the functional relevance of their targets.
Overall design Total RNA isolated from plasma samples of cystic fibrosis patients (n=5) and healthy controls (n=5) were used for miRNA microarray profiling
Contributor(s) Ideozu JE, Zhang X, Rangaraj V, McColley S, Levy H
Citation(s) 31664087
Submission date Jul 30, 2019
Last update date Nov 12, 2019
Contact name Justin Eze Ideozu
Organization name Lurie Children's Hospital
Department Human Molecular Genetics
Street address 255 E Chicago Avenue
City Chicago
State/province IL
ZIP/Postal code 60611
Country USA
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (10)
GSM3986272 Cystic fibrosis, biological rep1
GSM3986273 Cystic fibrosis, biological rep2
GSM3986274 Cystic fibrosis, biological rep3
BioProject PRJNA557469

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE135119_RAW.tar 6.6 Mb (http)(custom) TAR (of CEL)
GSE135119_normalized_data.txt.gz 97.3 Kb (ftp)(http) TXT
Processed data are available on Series record

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