|
| Status |
Public on Aug 22, 2019 |
| Title |
Nuclear Receptor Corepressor 1 (NCoR1) deletion changed the expression profile in cardiomyocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
NCoR1 played an important role in regulating the expression of many genes. We were wondering what kinds of genes the NCoR1 would regulate in cardiomyocytes. Therefore we generated the cardiomyocyte-specific NCoR1 knockout mice (CMNKO). Then we tried to analyze gene expression of left ventricular from littermate control (LC) and CMNKO mice with an unbiased way. Therefore the samples from left ventricular were subjected RNA-sequencing.
|
| |
|
| Overall design |
LV samples were collected from littermate control (LC) and cardiomyocyte-specific NCoR1 knockout (CMNKO) mice at the age of 2 months. Then the samples were sent for RNA sequencing.
|
| |
|
| Contributor(s) |
Duan S, Li C |
| Citation(s) |
31532577 |
| |
| Submission date |
Jul 26, 2019 |
| Last update date |
Nov 19, 2019 |
| Contact name |
Zhao V. Wang |
| E-mail(s) |
zhao.wang@utsoutherstern.edu
|
| Phone |
4693167040
|
| Organization name |
UT southwestern medical center
|
| Street address |
6000 Harry Hines Blvd
|
| City |
DALLAS |
| State/province |
TX |
| ZIP/Postal code |
75235 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (6)
|
| GSM3978930 |
WGC091220_Group A (LV from LC mice; A_15) |
| GSM3978931 |
WGC091581_Group A (LV from LC mice; A_25) |
| GSM3978932 |
WGC091582_Group A (LV from LC mice; A_26) |
| GSM3978933 |
WGC091221_Group B (LV from CMNKO mice; B_16) |
| GSM3978934 |
WGC091222_Group B (LV from CMNKO mice; B_17) |
| GSM3978935 |
WGC091223_Group B (LV from CMNKO mice; B_18) |
|
| Relations |
| BioProject |
PRJNA556813 |
| SRA |
SRP216477 |
Less...
More...