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| Status |
Public on Feb 24, 2020 |
| Title |
Transcriptomic analysis of the soleus muscle extracted from Dnm2 K562E point-mutant heterozygous mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA sequencing was performed to evaluate the impact of Dnm2 K562E mutation in the soleus muscle. The assessment of the dataset reveals a large number of differentially regulated transcripts between animals of both genotypes. This is consistent with a dominant phenotype caused by the Dnm2 K562E point mutation on the muscle.
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| Overall design |
The dataset includes sequenced RNA extracted from soleus muscle of mice aged to 2 months. Soleus muscles were obtained from 4 independent male mice per genotype. The genotypes analyzed include controls (Dnm2+/+) and Dnm2 K562E point-mutant mice (Dnm2 +/K562E).
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| Contributor(s) |
Pereira JA, Gerber J, Gerber D, Suter U |
| Citation(s) |
32129442 |
| |
| Submission date |
Jul 18, 2019 |
| Last update date |
May 26, 2020 |
| Contact name |
Jorge A. Pereira |
| E-mail(s) |
jorgea@ethz.ch
|
| Phone |
+41446333307
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| Organization name |
ETH Zurich
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| Department |
Dep. of Biology
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| Lab |
IMHS F25.2 - Suter Lab
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| Street address |
Otto-Stern-Weg 7
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| City |
Zurich |
| ZIP/Postal code |
8093 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA555329 |
| SRA |
SRP215262 |
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