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| Status |
Public on Dec 31, 2019 |
| Title |
Inflammatory Cytokines shape a Changing DNA Methylome in Monocytes Mirroring Disease Activity in Rheumatoid Arthritis (patients) |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
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| Summary |
Genome wide DNA methylation profiling of monocytes from healthy donors and rheumatoid arthritis patients. The Illumina Infinium MethylationEPIC Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in CD11b+CD33+CD15neg monocytes isolated from PBMCs of 17 healthy donors and 47 rheumatoid arthritis patients with different disease activity scores (DAS28).
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| Overall design |
Bisulphite converted DNA from the 64 samples were hybridised to the Illumina Infinium MethylationEPIC Beadchip.
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| Contributor(s) |
Rodríguez-Ubreva J, de la Calle-Fabregat C, Li T, Ciudad L, Ballestar ML, Català-Moll F, Morante-Palacios O, García-Gómez A, Celis R, Humby F, Nerviani A, Martín J, Pitzalis C, Cañete JD, Ballestar E |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 17, 2019 |
| Last update date |
Jan 01, 2020 |
| Contact name |
Esteban Ballestar |
| Organization name |
Josep Carreras Research Institute (IJC)
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| Lab |
Epigenetics and Immune Disease
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| Street address |
Ctra de Can Ruti, Camí de les Escoles s/n
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| City |
Badalona, Barcelona |
| State/province |
N/A = Not Applicable |
| ZIP/Postal code |
08916 |
| Country |
Spain |
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| Platforms (1) |
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| Samples (64)
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| Relations |
| BioProject |
PRJNA555087 |
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