|
| Status |
Public on May 11, 2020 |
| Title |
Temporal dissection of breast cancer brain metastases |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of this study was to identify temporal changes to breast cancer cells as they adapt to the brain metastatic microenvironment. MDA-MB-231-tdTomato human breast cancer cells were injected into the carotid artery of Rag1-/- mice and dissected at 7 or 40 days post injection for RNA-sequencing.
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| |
|
| Overall design |
3 samples were analyzed at 7 days post injection, and 9 samples were analyzed at 40 days post injection
|
| |
|
| Contributor(s) |
Zhang S, Howe E |
| Citation(s) |
32541798 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 CA194697 |
(PQD-3) Spatiotemporal Molecular Interrogation of Early Metastatic Evolution In Situ |
UNIVERSITY OF NOTRE DAME |
Siyuan Zhang |
|
| |
| Submission date |
Jul 17, 2019 |
| Last update date |
Aug 23, 2020 |
| Contact name |
Siyuan Zhang |
| E-mail(s) |
Siyuan.Zhang@UTSouthwestern.edu
|
| Phone |
214-648-6537
|
| Organization name |
UT Southwestern Medical Center
|
| Department |
Department of Pathology
|
| Street address |
6001 Forest Park Rd
|
| City |
Dallas |
| ZIP/Postal code |
75235 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA555055 |
| SRA |
SRP215018 |
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