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Status |
Public on Jan 16, 2024 |
Title |
Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin by biotinylated transposon (various cell lines I) |
Organisms |
Homo sapiens; Mus musculus |
Experiment type |
Other
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Summary |
This study introduced a method for directly identifying the transcriptional machinery on accessible chromatin (ATAC-MS) in a proteome scale. The goals of this study are to integrate ATAC-seq with ATAC-MS to investigate the real-time in vivo transcriptional regulatory processes in organisms.
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Overall design |
ATAC-seq was applied to identify changes in chromatin accessibility and transcription factors binding motifs in HeLa cells treated with TNFα, MCF7 treated with E2/4HT and C2C12 during differentiation.
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Contributor(s) |
Ding C, Zhang H |
Citation(s) |
34678055 |
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Submission date |
Jul 10, 2019 |
Last update date |
Jan 17, 2024 |
Contact name |
Haizhu Zhang |
E-mail(s) |
zhz2230@qq.com
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Phone |
18621062295
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Organization name |
Fudan University
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Department |
Institutes of Biomedical Sciences
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Lab |
He Fuchu Lab
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Street address |
No. 131 Dong'an Road, Xuhui District
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City |
Shanghai |
ZIP/Postal code |
200032 |
Country |
China |
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Platforms (2) |
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Samples (12)
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This SubSeries is part of SuperSeries: |
GSE174643 |
Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin by biotinylated transposon |
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Relations |
BioProject |
PRJNA553754 |
SRA |
SRP214100 |