|
| Status |
Public on Dec 23, 2019 |
| Title |
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency |
| Organism |
Mus musculus |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
Copy-number variation by Comparative Genomic Hybridization (CGH) on thymocytes and Kidney (control) of Tdp2+/+Atm-/- and Tdp2-/-Atm-/- mice.
|
| |
|
| Overall design |
6 independent experiments of Tdp2+/+Atm-/- mice and 3 independent experiments of Tdp2-/-Atm-/ mice.
|
| |
|
| Contributor(s) |
Álvarez-Quilón A, Terrón-Bautista J, Delgado-Sainz I, Serrano-Benítez A, Romero-Granados R, Martínez-García PM, Bernal-Lozano C, Quintero C, García-Quintanilla L, Cortés-Ledesma F |
| Citation(s) |
32060399 |
| |
| Submission date |
Jul 09, 2019 |
| Last update date |
Mar 02, 2020 |
| Contact name |
Felipe Cortés Ledesma |
| E-mail(s) |
fcortes@cnio.es
|
| Organization name |
CNIO
|
| Department |
Molecular Oncology
|
| Lab |
Topology and DNA breaks
|
| Street address |
Melchor Fernández Almagro 3
|
| City |
Madrid |
| State/province |
Madrid |
| ZIP/Postal code |
28029 |
| Country |
Spain |
| |
|
| Platforms (1) |
| GPL4094 |
Agilent-014699 Mouse Genome CGH Microarray 105A (G4416A) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA553571 |
Less...
More...