|
| Status |
Public on Dec 21, 2020 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of Bone Marrow-Derived Macrophage Transcriptomes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose:The purpose of this study is to detect activated or silenced genes during lncRNA-GMR-deficient Bone marrow-derived macrophages and the control cells. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis.Macrophages RNA profiles were generated by deep sequencing,using Illumina.
Results: We mapped about 10 million sequence reads per sample to the mouse genome, identified hundreds of genes with significant mRNA variation between lncRNA-GMR-deficient macrophages and the control cells.
|
| |
|
| Overall design |
Bone marrow-derived macrophage mRNA profiles of wild type (WT) and lncRNA-GMR -/- mice were generated by deep sequencing.
|
| |
|
| Contributor(s) |
Wang Y, Cao X |
| Citation(s) |
33326766 |
| |
| Submission date |
Jul 09, 2019 |
| Last update date |
Dec 21, 2020 |
| Contact name |
Yujia Wang |
| E-mail(s) |
halo4585@163.com
|
| Organization name |
Zhejiang University
|
| Street address |
Yuhangtang Road No.388
|
| City |
Hangzhou |
| ZIP/Postal code |
310058 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA553507 |
| SRA |
SRP213862 |
