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| Status |
Public on Sep 09, 2020 |
| Title |
Creld1-deficient CD4+ T cells under homeostatic condition and CD3/CD28 stimulation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Transciptome profiling of sorted naive CD4+ T cells from control or Creld1 conditional KO mice (CD4-Cre) both directly ex vivo and with or without stimulation with anti-CD3/anti-CD28 antibodies to study the impact of Creld1 on T cell biology
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| |
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| Overall design |
Conventional naïve CD4+ T cells from either Creld1 conditional knockout (CD4-Cre) or control mice as well as from eight-hour ex vivo cultures with or without T cell receptor stimulation by anti-CD3/anti-CD28 (n=3 / group)
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| |
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| Contributor(s) |
Bonaguro L, Schulte-Schrepping J, Ulas T, Haendler K, Schultze JL, Aschenbrenner AC |
| Citation(s) |
33169013 |
| |
| Submission date |
Jul 05, 2019 |
| Last update date |
Dec 09, 2020 |
| Contact name |
Joachim Schultze |
| E-mail(s) |
j.schultze@uni-bonn.de
|
| Organization name |
LIMES (Life and Medical Sciences Center Genomics and Immunoregulation)
|
| Department |
Genomics and Immunoregulation
|
| Street address |
Carl-Troll-Strasse 31
|
| City |
Bonn |
| State/province |
NRW |
| ZIP/Postal code |
53115 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (18)
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA552845 |
| SRA |
SRP213129 |
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