|
| Status |
Public on Aug 20, 2019 |
| Title |
LSD1 inhibition promotes epithelial differentiation through derepression of fate- determining transcription factors [proliferation vs differentiation] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Genome-wide gene expression changes triggered by Ca2+-induced differentiation of epidermal progenitors
|
| |
|
| Overall design |
In vitro cultured proliferating human epidermal progenitors were differentiated by treating cell cultures with 1.22mM CaCl2 for 48H.
|
| |
|
| Contributor(s) |
Egolf S, Aubert Y, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, Simpson C, Ridky T, Capell BC |
| Citation(s) |
31433976 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| K08 AR070289 |
Epigenomic mechanisms of skin carcinogenesis |
UNIVERSITY OF PENNSYLVANIA |
Brian Capell |
|
| |
| Submission date |
Jul 02, 2019 |
| Last update date |
Aug 22, 2019 |
| Contact name |
Yann Aubert |
| E-mail(s) |
yaubert@pennmedicine.upenn.edu
|
| Organization name |
University of Pennsylvania
|
| Department |
Penn Dermatology Research
|
| Lab |
Capell Lab
|
| Street address |
Biomedical Research Building 421 Curie Blvd
|
| City |
Philadelphia |
| State/province |
Pennsylvania |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
| GSE133766 |
LSD1 inhibition promotes epithelial differentiation through derepression of fate- determining transcription factors |
|
| Relations |
| BioProject |
PRJNA552360 |
| SRA |
SRP212801 |
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