|
| Status |
Public on Jun 20, 2019 |
| Title |
Bcl6 neurogenic activity in in vitro cortical progenitors [RNA-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Transcriptome analysis following Bcl6 induction (24h doxycycline) in mouse ES-cell-derived cortical progenitors (differentiation day 12) shows that Bcl6 promotes a neurogenic transcription program and represses selective genes of the main proliferative pathways.
|
| |
|
| Overall design |
RNA-seq screen for Bcl6-elicited gene expression changes in in vitro cortical progenitors (n=4)
|
| |
|
| Contributor(s) |
Bonnefont J, Tiberi L, Lefort A, Libert F, Vanderhaeghen P |
| Citation(s) |
31353074 |
| |
| Submission date |
Jun 19, 2019 |
| Last update date |
Sep 19, 2019 |
| Contact name |
Pierre Vanderhaeghen |
| E-mail(s) |
pierre.vanderhaeghen@kuleuven.vib.be
|
| Organization name |
VIB-KU Leuven
|
| Department |
Center for Brain & Disease Research
|
| Lab |
Stem cell and Developmental neurobiology
|
| Street address |
O&N4 Herestraat 49
|
| City |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
| |
|
| Platforms (1) |
| GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
|
| Samples (8)
|
|
| This SubSeries is part of SuperSeries: |
| GSE133032 |
Bcl6 binding sites and neurogenic activity in in vitro cortical progenitors |
|
| Relations |
| BioProject |
PRJNA549718 |
| SRA |
SRP201917 |
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