|
| Status |
Public on Oct 27, 2019 |
| Title |
The majority of A-to-I RNA editing is not required for mammalian homeostasis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNAseq of Adult Brain in ADAR1 E861A, ADAR2 knock out, ADAR1 E861A x ADAR2 knock out het, and ADAR1 E861A x ADAR2 knock out mice generated by deep sequencing.
|
| |
|
| Overall design |
Whole brain from 3 replicates of each genotype were subjected to RNA sequencing.
|
| |
|
| Contributor(s) |
Chalk AM, Heraud-Farlow JE, Taylor S, Gupte A, Walkley CR |
| Citation(s) |
31815657 |
| |
| Submission date |
Jun 05, 2019 |
| Last update date |
Feb 12, 2020 |
| Contact name |
Alistair Morgan Chalk |
| E-mail(s) |
achalk@svi.edu.au, alistair.chalk@gmail.com
|
| Organization name |
St Vincent's Institute of Medical Research
|
| Department |
Stem Cell Regulation Unit
|
| Lab |
Walkley
|
| Street address |
9 Princes st, Fitzroy
|
| City |
Melbourne |
| State/province |
VIC |
| ZIP/Postal code |
3065 |
| Country |
Australia |
| |
|
| Platforms (2) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL21273 |
HiSeq X Ten (Mus musculus) |
|
| Samples (15)
|
| GSM3854153 |
ADAR1 E861A ADAR2 KO Adult Brain - Whole. Replicate 1 (511) DKOr1 |
| GSM3854154 |
ADAR1 E861A ADAR2 KO Adult Brain - Whole. Replicate 2 (520) DKOr2 |
| GSM3854155 |
ADAR1 E861A ADAR2 KO Adult Brain - Whole. Replicate 3 (546) DKOr3 |
| GSM3854156 |
ADAR1 Het ADAR2 Het Adult Brain - Whole. Replicate 1 (510) Hetr1 |
| GSM3854157 |
ADAR1 Het ADAR2 Het Adult Brain - Whole. Replicate 2 (515) Hetr2 |
| GSM3854158 |
ADAR1 Het ADAR2 Het Adult Brain - Whole. Replicate 3 (547) Hetr3 |
| GSM3854159 |
ADAR1 WT ADAR2 KO Adult Brain - Whole. Replicate 1 (502) A2KOr1 |
| GSM3854160 |
ADAR1 WT ADAR2 KO Adult Brain - Whole. Replicate 2 (510) A2KOr2 |
| GSM3854161 |
ADAR1 WT ADAR2 KO Adult Brain - Whole. Replicate 3 (521) A2KOr3 |
| GSM3854162 |
ADAR1 E861A MDA5 knockout Adult Brain - Whole. Replicate 1 (401B) E861Ar1 [re-analysis] |
| GSM3854163 |
ADAR1 E861A MDA5 knockout Adult Brain - Whole. Replicate 2 (411B) E861Ar2 [re-analysis] |
| GSM3854164 |
ADAR1 E861A MDA5 knockout Adult Brain - Whole. Replicate 3 (413B) E861Ar3 [re-analysis] |
| GSM3854165 |
ADAR1 WT MDA5 knockout Adult Brain - Whole. Replicate 1 (75B) WTr1 [re-analysis] |
| GSM3854166 |
ADAR1 WT MDA5 knockout Adult Brain - Whole. Replicate 2 (82B) WTr2 [re-analysis] |
| GSM3854167 |
ADAR1 WT MDA5 knockout Adult Brain - Whole. Replicate 3 (84B) WTr3 [re-analysis] |
|
| Relations |
| BioProject |
PRJNA546532 |
| SRA |
SRP200481 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE132214_CountData.txt.gz |
1.0 Mb |
(ftp)(http) |
TXT |
| GSE132214_RAW.tar |
3.3 Mb |
(http)(custom) |
TAR (of TXT) |
| GSE132214_jacusa2_known_A2KO_vs_DKO.txt.gz |
658.7 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_E861A_vs_A2KO.txt.gz |
705.7 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_E861A_vs_WT.txt.gz |
642.8 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_Het_vs_A2KO.txt.gz |
879.2 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_Het_vs_DKO.txt.gz |
764.6 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_WT_vs_DKO.txt.gz |
657.8 Kb |
(ftp)(http) |
TXT |
| GSE132214_jacusa2_known_WTandHet_vs_DKO.txt.gz |
902.8 Kb |
(ftp)(http) |
TXT |
| GSE132214_supplemental_differential_expression.xlsx |
52.7 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
| Processed data provided as supplementary file |
Less...
More...