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| Status |
Public on Sep 07, 2020 |
| Title |
Longitudinal profiling of the human immune response to Plasmodium falciparum |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The diversity of human immune responses to P. falciparum is unknown and yet immune decision-making likely dictates outcome of infection
We infected 15 malaria-naïve human volunteers with P. falciparum and used longitudinal whole blood transcriptional profiling to independently analyse the immune response in every volunteer
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| |
|
| Overall design |
Timecourse analysis of the whole blood transcriptome in 15 malaria-infected human volunteers and 4 uninfected controls (120 samples in total, median = 6 samples per volunteer)
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| |
|
| Contributor(s) |
Spence P, Milne K, Ivens A |
| Citation(s) |
33648633 |
| |
| Submission date |
May 31, 2019 |
| Last update date |
Mar 11, 2021 |
| Contact name |
Alasdair Ivens |
| E-mail(s) |
al.ivens@ed.ac.uk
|
| Phone |
44 131 6513605
|
| Organization name |
Centre for Immunity, Infection and Evolution
|
| Street address |
Kings Buildings
|
| City |
Edinburgh |
| ZIP/Postal code |
EH9 3FL |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
| Samples (120)
|
|
| Relations |
| BioProject |
PRJNA545732 |
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