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Status |
Public on May 14, 2019 |
Title |
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages |
Organism |
Danio rerio |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Early and post-embryonic neural crest-derived lineages in the zebrafish trunk in response to thyroid hormone modulation
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Overall design |
Single-cell RNA-seq experiments were performed on the 10X Genomics platform from FAC sorted, Sox10:CRE positive cells from 5dpf and post-embryonic zebrafish trunks with and without thyroid hormone.
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Contributor(s) |
Saunders LM, Parichy DM, Trapnell C |
Citation(s) |
31140974, 33933422 |
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Submission date |
May 13, 2019 |
Last update date |
May 02, 2023 |
Contact name |
David Parichy |
Organization name |
University of Virginia
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Department |
Biology
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Street address |
409 McCormick Road, Department of Biology, PLSB 339
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City |
Charlottesville |
State/province |
VA |
ZIP/Postal code |
22903 |
Country |
USA |
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Platforms (1) |
GPL20828 |
Illumina NextSeq 500 (Danio rerio) |
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Samples (14)
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GSM3764566 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish trunks, biological replicate 1 |
GSM3764567 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish skins, biological replicate 2 |
GSM3764568 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish trunks, biological replicate 3 |
GSM3764569 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish trunks, biological replicate 4 |
GSM3764570 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish trunks, biological replicate 5 |
GSM3764571 |
Neural crest derived cells from euthyroid, post-embryonic zebrafish trunks, biological replicate 6 |
GSM3764572 |
Neural crest derived cells from hypothyroid, juvenile zebrafish trunks, biological replicate 1 |
GSM3764573 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish skins, biological replicate 2 |
GSM3764574 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish trunks, biological replicate 3 |
GSM3764575 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish trunks, biological replicate 4 |
GSM3764576 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish trunks, biological replicate 5 |
GSM3764577 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish trunks, biological replicate 6 |
GSM3764578 |
Neural crest derived cells from hypothyroid, post-embryonic zebrafish trunks, biological replicate 7 |
GSM3764579 |
Neural crest derived cells from 5 dpf , euthyroid zebrafish tails |
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Relations |
BioProject |
PRJNA542704 |
SRA |
SRP198298 |
Supplementary file |
Size |
Download |
File type/resource |
GSE131136_NC-deriv_5dpf_metadata.tsv.gz |
54.1 Kb |
(ftp)(http) |
TSV |
GSE131136_NC-deriv_eu_hypothyroid_metadata.tsv.gz |
551.3 Kb |
(ftp)(http) |
TSV |
GSE131136_all_NC_barcodes.tsv.gz |
122.0 Kb |
(ftp)(http) |
TSV |
GSE131136_all_NC_genes.tsv.gz |
205.3 Kb |
(ftp)(http) |
TSV |
GSE131136_all_NC_matrix.mtx.gz |
72.8 Mb |
(ftp)(http) |
MTX |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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