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Series GSE130969 Query DataSets for GSE130969
Status Public on Mar 15, 2020
Title Differential Gene expression of furin knockout (KO) DLD1, HCA7 and HT29 colorectal cancer cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We created furin KO cells in three colorectal cancer cell lines (DLD1, HCA7 and HT29) using CRISPR-Cas9 genome editing. And then we performed RNA-Seq analysis in furin KO colorectal cancer cells to identify potential effect of furin on gene expression patterns in DLD1, HCA7 and HT29 cells.
 
Overall design mRNA profiles of DLD1 cells (WT or furin KO), HCA7 cells (WT or furin KO) and HT29 cells (WT or furin KO) using RNA-Seq.
 
Contributor(s) He Z
Citation(s) 32139876
Submission date May 09, 2019
Last update date Mar 17, 2020
Contact name Zongsheng He
E-mail(s) hzshzb407@163.com
Organization name KU Leuven
Street address Herestraat 49
City Leuven
ZIP/Postal code 3000
Country Belgium
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (12)
GSM3757993 DLD1-WT - replicate1
GSM3757994 DLD1-WT - replicate2
GSM3757995 DLD1-Furin-KO- replicate1
Relations
BioProject PRJNA542145
SRA SRP197346

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130969_RAW.tar 3.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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