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Series GSE130909 Query DataSets for GSE130909
Status Public on Oct 27, 2021
Title Mouse liver H3K27ac histone marks in male and female mouse liver for two mouse strains: C57BL/6J and CAST/EiJ.
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Sequencing files provided here are mouse liver ChIP-seq for the activating histone mark H3K27ac in two mouse strains: C57BL/6J and CAST/EiJ. This is part of a larger study published in PLoS Genetics (2021) "Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model" that includes RNA-seq and DNase-seq in mouse liver from the same two strains. This allows us to identify strain-shared ("core") and strain-unique sex-biased genes and enhancers.
Overall design H3K27ac ChIP-seq in male and female mouse liver
Contributor(s) Matthews BJ, Waxman DJ
Citation(s) 34752452
NIH grant(s)
Grant ID Grant title Affiliation Name
R01 DK121998 Growth Hormone Regulation of Sex Differences in Liver Metabolism BOSTON UNIVERSITY CHARLES RIVER CAMPUS DAVID J WAXMAN
Submission date May 08, 2019
Last update date Nov 12, 2021
Contact name David J. Waxman
Organization name Boston University
Department Department of Biology and Bioinformatics Program
Street address 5 Cummington Mall
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (24)
GSM3756034 Male_B6_H3K27ac_Repl1_G162_M1
GSM3756035 Male_B6_H3K27ac_Repl2_G162_M2
GSM3756036 Male_B6_H3K27ac_Repl3_G162_M3
This SubSeries is part of SuperSeries:
GSE130914 Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model
BioProject PRJNA542216
SRA SRP197620

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130909_Female_B6_H3K27ac_merged_peaks.bed.gz 2.2 Mb (ftp)(http) BED
GSE130909_Female_CAST_H3K27ac_merged_peaks.bed.gz 2.2 Mb (ftp)(http) BED
GSE130909_Male_B6_H3K27ac_merged_peaks.bed.gz 2.1 Mb (ftp)(http) BED
GSE130909_Male_CAST_H3K27ac_merged_peaks.bed.gz 2.4 Mb (ftp)(http) BED
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Raw data are available in SRA
Processed data are available on Series record

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