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Status |
Public on May 08, 2019 |
Title |
Raptor determines β-cell identity and plasticity independent of metabolic state |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
In this study, we employed RNA-seq technology to identify the exact role of mTORC1 on β-cell identity and plasticity.
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Overall design |
β cell specific Raptor deficiency induced gene expression from purified β cells in mice with or without insulin pellets was measured at 4 weeks after the pellet implanted. β cells from WT mice were set as controls.
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Contributor(s) |
Ning G, Wang Q |
Citation(s) |
32439909 |
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Submission date |
May 07, 2019 |
Last update date |
Jun 01, 2020 |
Contact name |
Qinglei Yin |
E-mail(s) |
yinqinglei128@163.com
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Organization name |
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
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Street address |
Ruijin Second Road No.197
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City |
Shanghai |
ZIP/Postal code |
200025 |
Country |
China |
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Platforms (1) |
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Samples (11)
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Relations |
BioProject |
PRJNA541439 |
SRA |
SRP195742 |