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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Feb 17, 2020 |
| Title |
Impaired tumor death receptor signaling drives resistance to CAR T cell therapy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Other
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation(s) |
32001516, 35690611 |
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| Submission date |
May 03, 2019 |
| Last update date |
Jun 27, 2022 |
| Contact name |
Nathan Singh |
| E-mail(s) |
nathan.singh@wustl.edu
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| Phone |
4127164808
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| Organization name |
Washington University School of Medicine
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| Street address |
8008 Venetian Drive, 8008, 8008, 8008
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| City |
St. Louis |
| State/province |
MO |
| ZIP/Postal code |
63105 |
| Country |
USA |
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| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (45)
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| GSM3754712 |
CART19 cells, Nalm6 WT Stim rep 1 |
| GSM3754713 |
CART19 cells, Nalm6 WT Stim rep 2 |
| GSM3754714 |
CART19 cells, Nalm6 WT Stim rep 3 |
| GSM3754715 |
CART19 cells, Nalm6 BID KO Stim rep 1 |
| GSM3754716 |
CART19 cells, Nalm6 BID KO Stim rep 2 |
| GSM3754717 |
CART19 cells, Nalm6 BID KO Stim rep 3 |
| GSM3754718 |
CART19 cells, ATAC Resting rep 1 |
| GSM3754719 |
CART19 cells, ATAC Resting rep 2 |
| GSM3754720 |
CART19 cells, ATAC Resting rep 3 |
| GSM3754721 |
CART19 cells, ATAC Nalm6 WT Stim rep 1 |
| GSM3754722 |
CART19 cells, ATAC Nalm6 WT Stim rep 2 |
| GSM3754723 |
CART19 cells, ATAC Nalm6 WT Stim rep 3 |
| GSM3754724 |
CART19 cells, ATAC Nalm6 BID KO Stim rep 1 |
| GSM3754725 |
CART19 cells, ATAC Nalm6 BID KO Stim rep 2 |
| GSM3754726 |
CART19 cells, ATAC Nalm6 BID KO Stim rep 3 |
| GSM4649064 |
1_CR |
| GSM4649065 |
2_NR |
| GSM4649066 |
3_NR |
| GSM4649067 |
4_NR |
| GSM4649068 |
5_NR |
| GSM4649069 |
6_NR |
| GSM4649070 |
7_CR |
| GSM4649071 |
8_CR |
| GSM4649072 |
9_CR |
| GSM4649073 |
10_CR |
| GSM4649074 |
11_CR |
| GSM4649075 |
12_CR |
| GSM4649076 |
13_NR |
| GSM4649077 |
14_CR |
| GSM4649078 |
15_CR |
| GSM4649079 |
16_CR |
| GSM4649080 |
17_CR |
| GSM4649081 |
18_CR |
| GSM4649082 |
19_CR |
| GSM4649083 |
20_CR |
| GSM4649084 |
21_CR |
| GSM4649085 |
22_CR |
| GSM4649086 |
23_CR |
| GSM4649087 |
24_NR |
| GSM4649088 |
25_CR |
| GSM4649089 |
26_NR |
| GSM4649090 |
27_CR |
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| This SuperSeries is composed of the following SubSeries:
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| GSE130817 |
Transcriptional profiling of CART19 cells exposed to WT and BIDko Nalm6 cells |
| GSE130818 |
ATAC profiling of CART19 cells exposed to WT and BIDko Nalm6 cells |
| GSE130819 |
Genome-wide CRISPR/Cas9 guide library knockout screening in Nalm6 ALL cells under CART19 selective pressure |
| GSE153670 |
Bulk RNA sequencing from patient bone marrow samples |
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| Relations |
| BioProject |
PRJNA541515 |
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