|
| Status |
Public on May 02, 2019 |
| Title |
Obesity Remodels Activity and Transcriptional State of a Lateral Hypothalamic Brake on Feeding |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We demonstrate that high fat diet (HFD)-induced obesity alters the transcriptional state of lateral hypothalamic glutamate neurons in mice.
|
| |
|
| Overall design |
High-throughput single-cell RNA sequencing of lateral hypothalamic area (LHA) tissue in mice given ad libitum access to HFD or taste-matched control chow.
|
| |
|
| Contributor(s) |
Basiri ML, Rossi MA, Stuber GD |
| Citation(s) |
31249056 |
| |
| Submission date |
May 01, 2019 |
| Last update date |
Jan 06, 2020 |
| Contact name |
Marcus Luis Basiri |
| E-mail(s) |
marcus_basiri@med.unc.edu
|
| Organization name |
UNC Chapel Hill
|
| Lab |
Stuber Lab
|
| Street address |
115 Mason Farm Road
|
| City |
Chapel Hill |
| State/province |
NC |
| ZIP/Postal code |
27519 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA540713 |
| SRA |
SRP194426 |
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