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Series GSE130472 Query DataSets for GSE130472
Status Public on Apr 05, 2020
Title Gene expression analysis of Triple-negative breast tumors from young and aged mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Whole tissue RNA-seq analysis of mammary tumors from old (>12 months) and young (8-10 weeks) of mice after treatment with isotype, anti-CTLA4 or anti-PDL1 treatments.
 
Overall design To test in murine mammary tumors from young and old mice for the effects on gene expression of isotype (negative control), anti-CTLA4 and anti-PDL1 treatments. At least two seven replicates from each treatment were used in both pairwise and difference of differences fashions.
 
Contributor(s) Sceneay J, Hutchinson J, McAllister S
Citation(s) 31217296
Submission date Apr 30, 2019
Last update date Apr 05, 2020
Contact name Gregory James Goreczny
E-mail(s) ggoreczny@bwh.harvard.edu
Organization name Brigham & Women's Hospital
Street address 4 Blackfan Cir.
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (52)
GSM3739244 old_ctla4-1: Old_anti-CTLA4_treated_mammary_tumor_replicate_1
GSM3739245 old_ctla4-2: Old_anti-CTLA4_treated_mammary_tumor_replicate_2
GSM3739246 old_ctla4-3: Old_anti-CTLA4_treated_mammary_tumor_replicate_3
Relations
BioProject PRJNA540422
SRA SRP194231

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130472_rawcounts.csv.gz 2.0 Mb (ftp)(http) CSV
GSE130472_tpm.csv.gz 5.4 Mb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
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