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Series GSE130230 Query DataSets for GSE130230
Status Public on Jul 15, 2019
Title EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (ChIP-Seq)
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We identified a novel cofactor of PRC2, expresesd predominantly in the gonad, that lmits PRC2 enzymatic activity by impeding the interaction between the core complex and its accessory subunits.
Overall design We profiled the H3K27 histone mark in EED or CXORF67 mutants and WT in ipNF05.5 cells.
Contributor(s) Raggazini R, Pérez-Palacios R, Baymaz H, Zielinski D, Michaud A, Givelet M, Borsos M, Jansen PC, Servant N, Torres-Padilla ME, Bourc'his D, Fouchet P, Vermeulen M, Margueron R
Citation(s) 31451685
Submission date Apr 23, 2019
Last update date Sep 03, 2019
Contact name Nicolas Servant
Organization name Institut Curie
Street address 26 rue d'ulm
City Paris Cedex 05
ZIP/Postal code 75248
Country France
Platforms (2)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (28)
GSM3734215 U2OS_WT_1
GSM3734216 U2OS_WT_2
GSM3734217 U2OS_dEED_1
This SubSeries is part of SuperSeries:
GSE130231 EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
BioProject PRJNA534326
SRA SRP193558

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130230_RAW.tar 2.7 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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