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| Status |
Public on Jan 21, 2020 |
| Title |
RNA-sequencing of microglia, T cells and ILC2 from the brains of IL-33 treated aged (20-22mos) mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
ILC2 are potent producers of IL-5 and IL-13 and Th2 cytokines have been found to promote neurogenesis and cognitive functions. We report microglia, brain T cells and ILC2 have a range of differentially expressed genes in IL-33 treated aged mice. Brain ILC2 upregulated a range of neuroprotective genes.
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| Overall design |
We used Single-end 75 bp high throughput sequencing to detail the global programme of different gene expression between the microglia, T cells and ILC2 from the brains of IL-33 treated aged (20-22mos) mice.
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| Contributor(s) |
Yang Q, Fung IT |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 17, 2019 |
| Last update date |
Jan 21, 2022 |
| Contact name |
Qi Yang |
| E-mail(s) |
qy117@rwjms.rutgers.edu
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| Organization name |
Rutgers RWJMS
|
| Street address |
89 French St
|
| City |
New Brunswick |
| State/province |
NJ |
| ZIP/Postal code |
08901 |
| Country |
USA |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA533462 |
| SRA |
SRP192918 |
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