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| Status |
Public on Apr 01, 2020 |
| Title |
PRMT1-mediated FLT3 arginine methylation promotes FLT3-ITD+ Acute Myeloid Leukemia maintenance |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We want to obtain FLT3-ITD gene signature. To do so, we transduced CB CD34+ cells with mock or FLT3-ITD vectors and performed RNA sequencing (RNA-Seq).
Two Groups: Group1: CB CD34+ cells transduced with mock vector; Group2: CB CD34+ cells transduced with FLT3-ITD vector;
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| Overall design |
Expression profiling data in FLT3-ITD+ Cord blood cells were compared to corresponding control mock transduced cells by RNA-seq technology
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| |
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| Contributor(s) |
Li L, He X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 12, 2019 |
| Last update date |
Apr 01, 2020 |
| Contact name |
Xin He |
| E-mail(s) |
362792358@qq.com
|
| Organization name |
City of Hope
|
| Street address |
1500 E Duarte Rd
|
| City |
Duarte |
| ZIP/Postal code |
91010 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (4)
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| GSM3721570 |
CB CD34+ cells with FLT3-ITD-Replicate2 |
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| Relations |
| BioProject |
PRJNA532633 |
| SRA |
SRP192427 |
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