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| Status |
Public on Apr 09, 2019 |
| Title |
Identify signature genes associated with nanoparticle carrying IRF5 mRNA treatment in isolated peritoneal macrophages from ID8 cells-induced ovarian tumor mouse |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To identify signature genes associated with nanoparticles carrying IRF5 mRNA treatment on peritoneal macrophages, we analyzed 770 genes in 19 different pathways and processes across 7 different myeloid cell types.
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| Overall design |
In the study presented here, we performed genome analysis on isolated F4/80+, CD11b+ peritoneal macrophage from mice that from three treatment groups (1) two i.p. doses of PBS; (2) two i.p. doses of nanoparticles carrying 30 microgram of mIRF5 mRNA.
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| Contributor(s) |
Zhang F |
| Citation(s) |
31481662 |
| |
| Submission date |
Apr 08, 2019 |
| Last update date |
Sep 11, 2019 |
| Contact name |
Matthias Stephan |
| Organization name |
Fred Hutchinson Cancer Research Institute
|
| Street address |
1100 Fairview Ave. N., Thomas Research Buildin
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109-9024 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL25266 |
NanoString Mouse nCounter Myeloid Innate Immunity Panel NS_Mm_Myeloid_V2.0 |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA531507 |
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