|
| Status |
Public on Nov 20, 2020 |
| Title |
RNA-seq profiling of fibroblasts isolated from two distinct lung metastases stages and from normal lungs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We found that fibroblasts derived from lung metastases display specific gene signatures related to distinct functional enrichments, including stress, ECM remodelling, and inflammation.
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| |
|
| Overall design |
Fibroblasts were isolated from lungs of MMTV-PyMT;Col1a1-YFP mice at defined metastatic stages (micro-metastases, macro-metastases), and from age-matched normal control mice (FVB/n;Col1a1-YFP mice). RNA was isolated and RNA-seq was performed.
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| |
|
| Contributor(s) |
Shani O, Erez N |
| Citation(s) |
34169837 |
| |
| Submission date |
Mar 28, 2019 |
| Last update date |
Jul 14, 2021 |
| Contact name |
Neta Erez |
| E-mail(s) |
netaerez@tauex.tau.ac.il
|
| Organization name |
Tel Aviv University
|
| Department |
Pathology
|
| Lab |
Erez Lab
|
| Street address |
Haim Levanon
|
| City |
Tel Aviv Yaffo |
| ZIP/Postal code |
6997801 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (11)
|
|
| Relations |
| BioProject |
PRJNA529667 |
| SRA |
SRP189772 |
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