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| Status |
Public on Feb 06, 2019 |
| Title |
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression [microRNA] |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Using the highly sensitive miRCURYTM LNA Array, we screened 2081 microRNAs abundant 10 colorectal cancer (CRC) tissues and their corresponding normal-appearing tissues (NATs), and the function of differentially expressed microRNAs were analyzed by bioinformatics. The enrichment results indicated that these microRNAs perhaps participated in the occurrence and development process of colorectal cancer.
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| Overall design |
In this study, ten cases of colrectal cancer (CRC) tissues and their corresponding normal-appearing tissues (NATs) were used to acquire the microRNA expression profiling. The function of the differentially expressed microRNA were analyzed by bioinformatic methods. Finally,compared with the NATs，the expression of 341 microRNAs were up regulated,and 95 microRNAS were down regulated in colorectal cancer.
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| Contributor(s) |
Zhi Q, Wan D, Han Y, Xu Z, Ren R, Chen Z, Chen D |
| Citation(s) |
31300733 |
| |
| Submission date |
Feb 05, 2019 |
| Last update date |
Mar 26, 2020 |
| Contact name |
Qiaoming Zhi |
| E-mail(s) |
dv1988114@163.com
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| Phone |
8618826431370
|
| Organization name |
Soochow university
|
| Street address |
No.188 Shizi Road
|
| City |
Soochow |
| ZIP/Postal code |
215000 |
| Country |
China |
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| Platforms (1) |
| GPL18058 |
Exiqon miRCURY LNA microRNA array, 7th generation [miRBase v18, condensed Probe_ID version] |
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| Samples (20)
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| GSM3591526 |
miRNA_Patient1 corresponding normal-appearing tissue |
| GSM3591527 |
miRNA_Patient2 corresponding normal-appearing tissue |
| GSM3591528 |
miRNA_Patient3 corresponding normal-appearing tissue |
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| This SubSeries is part of SuperSeries: |
| GSE126095 |
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression |
|
| Relations |
| BioProject |
PRJNA521013 |
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