|
| Status |
Public on Feb 06, 2019 |
| Title |
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression [lncRNA/mRNAs] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Given the role of lncRNAs and mRNAs in tumor pathogenesis, we set out to identify transcripts that potentially drive colorectal tumorigenesis. In this study, we will use the microarray analysis to study the differences of the expression profiles of lncRNA and mRNA in colorectal cancer tissues, analyzing the differentially expressed genes by GO/KEGG enrichment, and predicting the new lncRNAs’ function.
|
| |
|
| Overall design |
To detect the lncRNA/mRNA expression profiles in 10 colorectal cancer (CRC) tissues and their corresponding normal-appearing tissues (NATs) by human lncRNA/mRNA expression profile chips and to identify the differentially expressed lncRNA/mRNA between CRC and their corresponding NATs based on the chip data. In this way, this study provided the basis for identifying novel CRC biomarkers and further studying the roles and functions of differentially expressed lncRNA/mRNA in CRC. The function of the differentially expressed lncRNA/mRNA were analyzed by bioinformatic methods.
|
| |
|
| Contributor(s) |
Zhi Q, Wan D, Han Y, Xu Z, Ren R, Chen D |
| Citation(s) |
31300733 |
| |
| Submission date |
Feb 05, 2019 |
| Last update date |
Mar 26, 2020 |
| Contact name |
Qiaoming Zhi |
| E-mail(s) |
dv1988114@163.com
|
| Phone |
8618826431370
|
| Organization name |
Soochow university
|
| Street address |
No.188 Shizi Road
|
| City |
Soochow |
| ZIP/Postal code |
215000 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL21047 |
Agilent-074348 Human LncRNA v6 4X180K [Probe Name Version] |
|
| Samples (20)
|
| GSM3591506 |
Patient1 corresponding normal-appearing tissue |
| GSM3591507 |
Patient2 corresponding normal-appearing tissue |
| GSM3591508 |
Patient3 corresponding normal-appearing tissue |
|
| This SubSeries is part of SuperSeries: |
| GSE126095 |
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression |
|
| Relations |
| BioProject |
PRJNA521015 |
Less...
More...