|
| Status |
Public on Jan 31, 2020 |
| Title |
Transcriptional signatures of progressive neuropathology in tau and amyloid mouse models |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using highly-parallel RNA-sequencing on samples from rTg4510 and J20 mice (n = 121 mice), collected at four different time points, we profiled transcriptional changes in the entorhinal cortex paralleling the progression of Alzheimer's disease-associated pathology.
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| |
|
| Overall design |
Highly parallel RNA-seq of the entorhinal cortex at four time points in transgenic (rTg4510 and J20) and wild type littermate control mice (n=121)
|
| |
|
| Contributor(s) |
Castanho I, Mill J |
| Citation(s) |
32049030 |
| |
| Submission date |
Jan 31, 2019 |
| Last update date |
Feb 24, 2020 |
| Contact name |
Jonathan Mill |
| E-mail(s) |
J.Mill@exeter.ac.uk
|
| Organization name |
University of Exeter Medical School
|
| Street address |
RILD Building, RD&E Hospital, Barrack Rd
|
| City |
Exeter |
| ZIP/Postal code |
EX2 5DW |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (121)
|
|
| Relations |
| BioProject |
PRJNA518104 |
| SRA |
SRP183070 |
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