|
| Status |
Public on Jan 26, 2020 |
| Title |
Transcriptomic analysis of LSD1i-sensitive and resistant AML cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of this study is to identify the molecular mechanisms underlying the resistance/sensitivity of AML cells to lysine specific demethylase 1 (LSD1) inhibitor.
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| Overall design |
We performed the transcriptomic analysis at the earliest detected and last tested time points in which mTOR was regulated secondary to LSD1i (i.e. 6 and 72h in sensitive KASUMI-1 cells and 24 and 72h in resistant THP-1 cells)
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| |
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| Contributor(s) |
Abdel-Aziz AK |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 27, 2019 |
| Last update date |
Jan 28, 2020 |
| Contact name |
Saverio Minucci |
| Organization name |
European Institute of Oncology
|
| Street address |
via Adamello 16
|
| City |
milano |
| ZIP/Postal code |
20139 |
| Country |
Italy |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA517344 |
| SRA |
SRP182609 |
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