 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Jul 12, 2021 |
| Title |
Development of novel diagnostic system for pancreas cancer including early stages measuring mRNA of whole blood cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The aim of the study is the assessment of diagnostic efficacy of extracorporeal diagnostic reagent pancreatic cancer diagnosis kit whose principle is the measurement of gene expression affected in pancreatic cancer human patients. Clinical trial registration number: UMIN000020758.
|
| |
|
| Overall design |
Development of a blood mRNA pancreatic ductal adenocarcinoma (PDAC) screening system using real-time detection PCR to detect the expression of specific genes, in order to discriminate PDAC from healthy volunteers. We performed a clinical study to assess the performance of the developed system. We collected whole blood RNA from PDAC patients and non-cancer subjects. The sensitivity of the system for PDAC diagnosis and the specificity for non-cancer volunteers were determined for the evaluation of the screening system.
Contributed by Hokuriku Liver Study Group
|
| |
|
| Contributor(s) |
Sakai Y, Honda M, Matsui S, Komori O, Murayama T, Fujiwara T, Mizuno M, Imai Y, Yoshimura K, Nasti A, Wada T, Iida N, Kitahara M, Horii R, Toshikatsu T, Nishikawa M, Okafuji H, Mizukoshi E, Yamashita T, Yamashita T, Arai K, Kitamura K, Kawaguchi K, Takatori H, Shimakami T, Terashima T, Hayashi T, Nio K, Kaneko S |
| Citation(s) |
30742728 |
| |
| Submission date |
Jan 16, 2019 |
| Last update date |
Jul 13, 2021 |
| Contact name |
Yoshio Sakai |
| E-mail(s) |
yoshios@m-kanazawa.jp
|
| Phone |
+81-76-265-2235
|
| Organization name |
Kanazawa University
|
| Department |
Department of Gastroenterology
|
| Street address |
13-1 Takara-machi
|
| City |
Kanazawa |
| State/province |
Ishikawa |
| ZIP/Postal code |
920-8641 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
|
| Samples (30)
|
|
| Relations |
| BioProject |
PRJNA515428 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE125158_RAW.tar |
64.6 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...