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GEO help: Mouse over screen elements for information. |
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| Status |
Public on May 31, 2019 |
| Title |
Genome-wide expression profiling of Uhrf1hepKO mouse livers at baseline and following PHx |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This study was carried out to investigate the mechanism behind the enhanced liver regenerative response observed in Uhrf1hepKO mice. Livers was collected at baseline and at 24hrs, 30hrs, 40hrs, 48hrs, 96hrs, 7days and 4 weeks following 2/3 partial hepatectomy surgery (PHx). These timepoints correspond to key cell cycle events that occur following PHx as established in literature.
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| Overall design |
RNA was extracted using column based methods (Zymo DNA/RNA Duet Kit). Libraries were prepared according to Illumina Truseq RNA sample prep kit (PolyA)
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| Contributor(s) |
Wang S, Sadler Edepli K |
| Citation(s) |
31231040 |
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| Submission date |
Jan 12, 2019 |
| Last update date |
Sep 01, 2021 |
| Contact name |
Kirsten Sadler Edepli |
| E-mail(s) |
kirsten.edepli@nyu.edu
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| Phone |
971568327587
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| Organization name |
New York University Abu Dhabi
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| Department |
Biology
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| Street address |
PO Box 129188
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| City |
Abu Dhabi |
| State/province |
Abu Dhabi |
| ZIP/Postal code |
000 |
| Country |
United Arab Emirates |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (45)
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| GSM3561057 |
Uhrf1hepKO, PHx, 24hrs rep 1 |
| GSM3561058 |
Uhrf1hepKO, PHx, 24hrs rep 2 |
| GSM3561059 |
Uhrf1hepKO, PHx, 24hrs rep 3 |
| GSM3561060 |
WT, PHx, 30hrs rep 2 |
| GSM3561061 |
WT, PHx, 30hrs rep 3 |
| GSM3561062 |
Uhrf1hepKO, PHx, 30hrs rep 1 |
| GSM3561063 |
Uhrf1hepKO, PHx, 30hrs rep 2 |
| GSM3561064 |
Uhrf1hepKO, PHx, 30hrs rep 3 |
| GSM3561065 |
WT, baseline rep 1 |
| GSM3561066 |
WT, baseline rep 2 |
| GSM3561067 |
WT, baseline rep 3 |
| GSM3561068 |
KO, baseline rep 1 |
| GSM3561069 |
KO, baseline rep 2 |
| GSM3561070 |
KO, baseline rep 3 |
| GSM3561071 |
WT, PHx, 40hrs rep 1 |
| GSM3561072 |
WT, PHx, 40hrs rep 2 |
| GSM3561073 |
WT, PHx, 40hrs rep 3 |
| GSM3561074 |
Uhrf1hepKO, PHx, 40hrs rep 1 |
| GSM3561075 |
Uhrf1hepKO, PHx, 40hrs rep 2 |
| GSM3561076 |
Uhrf1hepKO, PHx, 40hrs rep 3 |
| GSM3561077 |
WT, PHx, 48hrs rep 2 |
| GSM3561078 |
WT, PHx, 48hrs rep 3 |
| GSM3561079 |
Uhrf1hepKO, PHx, 48hrs rep 1 |
| GSM3561080 |
Uhrf1hepKO, PHx, 48hrs rep 2 |
| GSM3561081 |
Uhrf1hepKO, PHx, 48hrs rep 3 |
| GSM3561082 |
WT, PHx, 96hrs rep 1 |
| GSM3561083 |
WT, PHx, 96hrs rep 2 |
| GSM3561084 |
WT, PHx, 96hrs rep 3 |
| GSM3561085 |
Uhrf1hepKO, PHx, 96hrs rep 1 |
| GSM3561086 |
Uhrf1hepKO, PHx, 96hrs rep 2 |
| GSM3561087 |
Uhrf1hepKO, PHx, 96hrs rep 3 |
| GSM3561088 |
WT, PHx, 7days rep 1 |
| GSM3561089 |
WT, PHx, 7days rep 2 |
| GSM3561090 |
WT, PHx, 7days rep 3 |
| GSM3561091 |
Uhrf1hepKO, PHx, 7days rep 1 |
| GSM3561092 |
Uhrf1hepKO, PHx, 7days rep 3 |
| GSM3561093 |
WT, PHx, 4wks rep 1 |
| GSM3561094 |
WT, PHx, 4wks rep 2 |
| GSM3561095 |
WT, PHx, 4wks rep 3 |
| GSM3561096 |
Uhrf1hepKO, PHx, 4wks rep 1 |
| GSM3561097 |
Uhrf1hepKO, PHx, 4wks rep 2 |
| GSM3561098 |
Uhrf1hepKO, PHx, 4wks rep 3 |
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| This SubSeries is part of SuperSeries: |
| GSE125008 |
Epigenetic compensation promotes liver regeneration |
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| Relations |
| BioProject |
PRJNA514876 |
| SRA |
SRP178903 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE125007_Gene_FPKMs.csv.gz |
3.5 Mb |
(ftp)(http) |
CSV |
| GSE125007_Gene_counts.csv.gz |
1.1 Mb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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