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| Status |
Public on Jun 06, 2019 |
| Title |
Genome-wide profiling for h3k4me3, h3k27me3, and h3k9me3 in Uhrf1hepKO mouse livers |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This study was carried out to investigate potential changes in the genome-wide distribution of h3k4me3, h3k27me3, and h3k9me3 in Uhrf1hepKO mouse livers compared to wild-type.
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| |
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| Overall design |
ChIP was carried out to pull down h3k4me3, h3k27me3, or h3k9me3 bound chromatin from nuclei isolated from wild-type and Uhrf1hepKO liver tissues. This chromatin fraction was then digested using micrococcal nuclease to release mononucleosomes. DNA fragments purified from nucleosomes were then used to generate libraries and sequenced.
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| |
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| Contributor(s) |
Kirsten S, Zhang C, Sadler (Edepli) KC |
| Citation(s) |
31231040 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 DK080789 |
Epigenetic Regulation of Development and Liver Regeneration by UHRF1 |
NEW YORK UNIVERSITY |
Kirsten C Sadler Edepli |
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| |
| Submission date |
Jan 12, 2019 |
| Last update date |
Nov 04, 2021 |
| Contact name |
Kirsten Sadler Edepli |
| E-mail(s) |
kirsten.edepli@nyu.edu
|
| Phone |
971568327587
|
| Organization name |
New York University Abu Dhabi
|
| Department |
Biology
|
| Street address |
PO Box 129188
|
| City |
Abu Dhabi |
| State/province |
Abu Dhabi |
| ZIP/Postal code |
000 |
| Country |
United Arab Emirates |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (15)
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| This SubSeries is part of SuperSeries: |
| GSE125008 |
Epigenetic compensation promotes liver regeneration |
|
| Relations |
| BioProject |
PRJNA514875 |
| SRA |
SRP178902 |
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