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| Status |
Public on Jan 09, 2019 |
| Title |
First global gene expression profile analysis of the intestinal stem cell (ISC) niche of SAMP/YitFc (SAMP) mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
High-throughput RNA-seq approach was used to profile transcriptional ISC niche responses in SAMP mice versus healthy controls (AKR)
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| Overall design |
The RNA-seq transcriptional analysis was performed on ISC niche laser captured from small intestine using three independent samples (biological replicates) of each mouse group with defined total inflammatory score: ileal ISC niches from inflammation-free SAMP-5 (5-wk old) and AKR-25 (25-wk old) mice, and from highly diseased SAMP-25 mice (25-wk old) with Crohn's disease-like ileitis.
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| |
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| Contributor(s) |
Buttό LF, Dave M |
| Citation(s) |
32679063 |
| |
| Submission date |
Jan 08, 2019 |
| Last update date |
Aug 24, 2020 |
| Contact name |
Ludovica Buttó |
| E-mail(s) |
lxb326@case.edu
|
| Phone |
2163680756
|
| Organization name |
CWRU
|
| Street address |
2109 ADELBERT ROAD
|
| City |
Cleveland |
| State/province |
OH |
| ZIP/Postal code |
44106 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA513868 |
| SRA |
SRP176645 |
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