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Series GSE124536 Query DataSets for GSE124536
Status Public on Jan 02, 2022
Title A wave of Foxp3 + regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The liver in newborn animals undergo a maturation process in order to adapt to a plethora of changes and challenges in the extra-uterine life. The influx of regulatory T cells during 1-2-week period protect the animals from autoimmune hepatitis and govern the transformation of a neonatal liver to a crucial metabolic organ in adults.
Overall design CD4+GFP+ Treg cells from the liver and spleen of Foxp3GFP knock-in mice (12-day-old) were purified by flow cytometry.
Contributor(s) Li M, Zhang K, Ge Q
Citation(s) 31171863
Submission date Jan 02, 2019
Last update date Apr 03, 2022
Contact name Kunshan Zhang
Organization name Tongji University
Department Tongji Hospital
Lab Translational Stem Cell Research Center
Street address 389 Xincun Rd.
City Shanghai
ZIP/Postal code 200064
Country China
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (6)
GSM3536119 A1
GSM3536120 A2
GSM3536121 A3
BioProject PRJNA512452
SRA SRP174990

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Supplementary file Size Download File type/resource
GSE124536_counts.table.txt.gz 215.0 Kb (ftp)(http) TXT
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Processed data are available on Series record
Raw data are available in SRA

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